Niacin (Nicotinic acid), chemical name pyridine-3-formic acid, is an organic compound, chemical formula C6H5NO2, for the white crystalline powder, mainly in animal viscera, muscle tissue, fruit, egg yolk also exists in trace amounts, is one of the 13 vitamins necessary for the human body. Niacin is mainly used as a feed additive, which can improve the utilization rate of feed protein, improve milk production of dairy cows and meat production and quality of fish, chicken, duck, cattle, sheep and other livestock. Nicotinic acid is also a widely used pharmaceutical intermediates, using it as raw materials, can be synthesized a variety of medicines, such as nicosamine and nicotinate inositol ester. In addition, niacin also plays an irreplaceable role in luminous materials, dyes, electroplating industry and other fields.
| Product Name |
Niacin/ Nicotinic acid |
| Purity |
99.0%min |
| Product Grade |
Food Grade; Pharmaceutical Grade |
| Classification |
Vitamins |
| Appearance |
White crystalline powder |
Application of niacin in the field of pharmaceutical synthesis
Niacin, as a drug, can prevent skin diseases and similar vitamin deficiencies, has the effect of dilating blood vessels, and is used to treat peripheral nerve spasm, arteriosclerosis and other diseases. Nicotinic acid can also be used as a pharmaceutical intermediate to synthesize a variety of amides and esters with important medical uses, such as nicotinamide can be used to treat intestinal diseases, hydroxymethylamine nicotinate is a good medicine for liver, gallbladder and bacteriostatic bacteria, and nicotinoylbenzoylamine can be used to prevent and control schistosomiasis as an efficient snail killing drug. Niacin and tropanol can be synthesized to treat circulatory disorders, vitamin B deficiency, slossitis, hypertension and other diseases. Nicoxamide synthesized from niacin and diethylamine is a central nervous stimulant used in the treatment of central respiratory and circulatory system failure. Nicotinic acid and alcohol reaction to produce nicotinic acid inositol ester, is the treatment of hyperlipidemia, coronary heart disease, migraine, peripheral vascular disorders and other drugs. [2]
Application of niacin as auxiliaries
Niacin is an indispensable food and feed additive for human and animal growth. Therefore, niacin is widely used as an additive in pastries, dairy products, corn flour, etc. Niacin can also be used in combination with vitamins to replace some nitrite as a deodorant or preservative in meat products, in addition, niacin can also be used as a fresh-keeping agent for vegetables. Since a large part of niacin exists in the complex form in grain feed, it cannot be directly absorbed by animals, so the method commonly used in the world is to add synthetic niacin to the feed. It has been proved by feed feeding experiment that the synthetic niacin can be absorbed and utilized by animals 100%, and can achieve obvious weight gain effect in a short time. According to the situation of the breeding industry in China, the standard for adding niacin in China is: the amount of niacin per kg of pig feed (dry base) is 9-24mg, and the amount of niacin per kg of chicken feed (dry base) is 10-27mg.
Food additive
Niacin belongs to the vitamin B group and is involved in the body's lipid metabolism, oxidation and anaerobic decomposition processes. Niacin can be converted from tryptophan in the body, and the human body is generally not prone to niacin deficiency, but when the staple food does not contain niacin, or there is a substance that breaks down niacin in the staple food, it is easy to cause crude skin diseases caused by the lack of niacin. Therefore, niacin is widely used in pasta processing, dairy products and corn meal production. Adding a certain amount of niacin to food can effectively prevent the occurrence of such diseases.
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